Gum Disease Linked to Colorectal Cancer: COLDENT Study

A recently published article including the results of a 7 year study from Montreal, Canada reveals that individuals with a history of periodontal disease have an increased risk for colorectal cancer. Over the course of the study, individuals with a history of periodontal disease had a 1.45 times increased risk of developing a new colorectal cancer diagnosis, compared to those who did not have a history of periodontal disease.

The researchers believe that the "putative mechanism of periodontal disease and cancer association involves the spread of periodontal pathogens to extra-oral sites, dissemination of bacteria endotoxins, and release of inflammation products directly into the bloodstream."

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For access to the article: https://rdcu.be/cNkw0

Idrissi Janati, A., Karp, I., Latulippe, JF. et al. Periodontal disease as a risk factor for sporadic colorectal cancer: results from COLDENT study. Cancer Causes Control 33, 463–472 (2022). https://doi.org/10.1007/s10552-021-01541-y